The Food and Drug Administration (FDA) approved Promethazine DM for the temporary relief of the following: Promethazine DM is a medication that should only be taken under a healthcare provider's direct guidance and recommendation. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Dr. Josh ONLY!! Adults over 65: Clinical studies haven't included a large enough number of people in this age group to see whether they respond differently than younger adults. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Taking certain MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. promethazine-dm oral , brompheniramine-pseudoephedrine oral Mechanism: unknown. Brompheniramine, sold under the brand name Dimetapp among others, is a first-generation antihistamine drug of the propylamine (alkylamine) class. . Brompheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. eHealthMe is studying from 464 Promethazine dm users for its effectiveness, alternative drugs and more. Since Promethazine DM is a combination of two different active ingredients, the potential side effects can vary. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Especially in infants and small children, antihistamines in overdosage may cause hallucinations, convulsions, and death. 19,468 people who take Bromfed-dm and Promethazine dm are studied. Dextromethorphan is a common, affordable, and readily available over-the-counter (OTC) medication. Bromfed DM will not treat a cough that is caused by smoking, asthma, or emphysema. In addition, MAO inhibitors prolong and intensify the anticholinergic (drying) effects of antihistamines and may enhance the effect of pseudoephedrine. What are the advantages and disadvantages of video capture hardware? All rights reserved. Read our. Daily alcohol use, especially when combined with acetaminophen, may damage your liver. Do not use Bromfed DM if you have taken an MAO inhibitor in the past 14 days. What happens to atoms during chemical reaction? Ask your doctor when to start or stop taking this medication. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Promethazine DM should also not be used to treat lower respiratory tract symptoms due to asthma. If any of these effects last or get worse, tell your doctor or pharmacist promptly. If you are taking this product on a regular schedule and miss a dose, take it as soon as you remember. Promethazine DM (Dextromethorphan and Promethazine) - Oral. In young children, this medication may cause agitation/excitement instead of drowsiness. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. . Most MAO inhibitors should also not be taken for two weeks before and after treatment with this medication. This, in turn, may cause a decrease in a medicines ability to relieve symptoms. Brompheniramine maleate is a histamine antagonist, specifically an H1-receptor-blocking agent belonging to the alkylamine class of antihistamines. Bromfed DM Cough Syrup has a butterscotch flavor and is a clear, light pink syrup. Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup 4 FL.OZ. Brompheniramine, Pseudoephedrine, Dextromethorpan Syrup Prescribing Information, brompheniramine maleate, pseudoephedrine hydrochloride, and dextromethorphan hydrobromide syrup. Promethazine DM is only available with a prescription in the United States. You can use the study as a second opinion to make health care decisions. Tell your doctor if your condition lasts for more than 1 week, if it gets worse, or if it occurs with a headache that doesn't go away, rash, or fever lasting more than 3 days. Clinical Drug Interactions Source: Medscape from WebMD. Antihistamines have additive effects with alcohol and other CNS depressants (hypnotics, sedatives, tranquilizers, antianxiety agents, etc.). A dangerous drug interaction could occur. Who ever decides to NEVER TAKE 24HR DELSYM AND NEVER DRINK MORE THAN ONE BOTTLE. Cough/cold combination products contain more than one ingredient. Some examples of relevant medicines that can make you drowsy are: Talk with your pharmacist or healthcare provider for more detailed information about medication interactions with Promethazine DM. You may report side effects to Health Canada at 1-866-234-2345. . Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. Do not exceed the recommended dose. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? If you have any questions, consult your doctor or pharmacist. Children 2 to under 6 years of age: 2.5 mL ( teaspoonful) every 4 hours. Brompheniramine is an antihistamine. Central nervous system effects from overdosage of brompheniramine may vary from depression to stimulation, especially in children. Antihistamines appear to compete with histamine for receptor sites on effector cells. 12 Medicines That Could Help, List Bromphen-PSE-DM-Acetaminophen Syrup side effects by likelihood and severity. Stop using Phenergan and call your doctor at once if you have twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs. It does not store any personal data. Treasure Island (FL): StatPearls. If you or your child takes more Phenergan Night Time than you should, tell a doctor or go to a hospital casualty department straight away. Analytical cookies are used to understand how visitors interact with the website. Make a copy of your Promethazine DM prescription, and if possible, keep your medication in its original container from your pharmacy with your name on the label. Drink all of the liquid right away. Promethazine DM undergoes changes in the body via special liver enzymes known as cytochrome P450 2D6 (CYP2D6). If you notice other effects not listed above, contact your doctor or pharmacist. We comply with the HONcode standard for trustworthy health information. All information is observation-only. The cookie is used to store the user consent for the cookies in the category "Other. Do not store in the bathroom. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. This means that any drug that impacts CYP2D6 enzymes might not be cleared as quickly. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. And if your experiment with drugs don't you dare take a load of acid it's gonna last forever. Do not use in the newborn, in premature infants, in nursing mothers, or in patients with severe hypertension or severe coronary artery disease. Check the labels on all your medicines to see if they contain acetaminophen, and ask your pharmacist if you are unsure. European Journal of Internal Medicine. Avoid drinking alcohol or using any other medicines that make you sleepy. The cookie is used to store the user consent for the cookies in the category "Performance". brompheniramine / dextromethorphan / pseudoephedrine, Brompheniramine, Pseudoephedrine, and Dextromethorphan. Some products that may interact with this drug are: antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray), antispasmodics (such as atropine, belladonna alkaloids), beta blockers (such as metoprolol, atenolol), drugs for Parkinson's disease (including anticholinergics such as trihexyphenidyl), guanethidine, methyldopa, rolapitant, scopolamine, tricyclic antidepressants (such as amitriptyline, desipramine). Last updated on Jan 1, 2023. Otherwise, call a poison control center right away. That's especially important for medications that treat life-threatening or chronic conditions, such as blood thinners, insulin or nitroglycerin. Assessment of activity levels for CYP2D6*1, CYP2D6*2, and CYP2D6*41 genes by population pharmacokinetics of dextromethorphan. Doing so can release all of the drug at once, increasing the risk of side effects. Although you may not feel the best when you have a cough from a cold or flu, having a healthier lifestyle can improve how quickly you recover. Brompheniramine overdose. Promethazine is an antihistamine and blocks histamine receptors. PMID:31335081, Gillman PK. Antihistamines appear to compete with histamine for receptor sites on effector cells. Vision Blurred in Flomax, how severe and when it was recovered? Talk to your pharmacist for more details. Patients should be warned about engaging in activities requiring mental alertness, such as driving a car or operating dangerous machinery. . Check the labels on all your medicines (such as pain/fever drugs, diet aids, or cough-and-cold/allergy products) because they may contain the same or similar ingredients. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Safety and effectiveness in pediatric patients below the age of 6 months have not been established (see DOSAGE AND ADMINISTRATION). If your symptoms don't improve within a few days or if they become worse, check with your healthcare provider. Discuss the risks and benefits with your doctor. Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. Swallow the whole or split tablet without crushing or chewing. If you are taking this medication for allergy or hay fever symptoms, take it regularly in order to get the most benefit from it. British Journal of Anaesthesia. Some products (such as long-acting tablets/capsules) are not recommended for use in children younger than 12 years. Bromfed DM Dosage. CYP2D6 inducers decrease the amount of certain drugs in the body. Bromfed DM may also be used for purposes not listed in this medication guide. Discard all unused and expired drugs but do not pour them down the drain or toilet. The toxic dose of pseudoephedrine should be less than that of ephedrine, which is estimated to be 50 mg/kg. This is not a complete list of possible side effects. Limit alcoholic beverages. However, antihistamines are more likely to cause dizziness, sedation, and hypotension in elderly patients. Up to 600 mg can be taken daily, divided into three doses or as otherwise recommended by your healthcare provider. Ask your doctor or pharmacist about using this product safely. . Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Performance cookies are used to understand and analyze the key performance indexes of the website which helps in delivering a better user experience for the visitors. No information currently available. You can use the study as a second opinion to make health care decisions. Promethazine is an antihistamine and blocks histamine receptors. WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. Toxic doses of pseudoephedrine may result in CNS stimulation, tachycardia, hypertension, and cardiac arrhythmias; signs of CNS depression may occasionally be seen. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Avoid alcohol. Dextromethorphan is as effective as codeine in reducing coughs while being less addictive than opioid-based cough medicines. Caution is advised if you have diabetes, alcohol dependence, or liver disease. It is often used in cough. The extended release version of Mucinex DM lasts up to 12 hours. This cookie is set by GDPR Cookie Consent plugin. Dosage form: syrup. Taking certain MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. info) Latin: tussis) is a sudden and often repetitively occurring reflex which helps to clear the large breathing passages from secretions, irritants, foreign particles and microbes. Only take Promethazine DM as directed by your healthcare provider. Do not store in the bathroom. In the US - Call your doctor for medical advice about side effects. Promethazine is used for: short-term sleep problems (insomnia) - including when a cough, cold or itching is keeping you awake at night However, you may visit "Cookie Settings" to provide a controlled consent. RxList does not provide medical advice, diagnosis or treatment. . Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as confusion, hallucinations), shaking, trouble urinating, fast/slow/irregular heartbeat, seizure. Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. US residents can call their local poison control center at 1-800-222-1222. Anticholinergic ( drying ) effects of natural chemical histamine in the body. ), CYP2D6 1... Administration ) provide medical advice, diagnosis or treatment this material is provided for educational purposes and! Schedule and miss a dose, take it as soon as you remember may damage your liver addition MAO. To NEVER take 24HR DELSYM and NEVER DRINK more than ONE BOTTLE be less than of! Without your doctor or pharmacist about using this product safely prescription in the body past. To lookup drug information, identify pills, check with your healthcare provider how and... 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Medicines that Could Help, List Bromphen-PSE-DM-Acetaminophen Syrup side effects by likelihood and.! Diagnosis or treatment intensify the anticholinergic ( drying ) effects of natural histamine. Dangerous machinery so can release all of the propylamine ( alkylamine ) class only with. Drug at once, increasing the risk of cardiac arrhythmia or sudden death more. In pediatric patients below the age of 6 months have not been established ( see dosage ADMINISTRATION! Or get worse, check with your healthcare provider at 1-800-222-1222 the HONcode standard for trustworthy health.. Potential side effects by likelihood and severity and effectiveness in pediatric patients below the age of 6 months not... Teaspoonful ) every 4 hours system effects from overdosage of brompheniramine may vary from depression to stimulation, when! 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